Showing posts with label spike protein. Show all posts
Showing posts with label spike protein. Show all posts

Monday, December 25, 2023

Presence of viral spike protein and vaccinal spike protein in the blood serum of patients with long-COVID syndrome

 K. Dhuli, M.C. Medori, C. Micheletti, K. Donato, F. Fioretti, A. Calzoni, A. Praderio, M.G. De Angelis, G. Arabia, S. Cristoni, S. Nodari, M. Bertelli

MAGI’S LAB, Rovereto, Trento, Italy. kristjana.dhuli@assomagi.org


OBJECTIVE: COVID-19 patients experience, in 10-20% of the cases, a prolonged long-COVID syndrome, defined as the persistence of symptoms for at least two months after the infection. The underlying biological mechanisms of this syndrome remain poorly understood. Several hypotheses have been proposed, among which are the potential autoimmunity resulting from molecular mimicry between viral spike protein and human proteins, the reservoir and viral reproduction hypothesis, and the viral integration hypothesis. Although official data state that vaccinal spike protein is harmless and remains at the site of infection, several studies proposed spike protein toxicity and found it in blood circulation several months after the vaccination. To search for the presence of viral and vaccine spike protein in a cohort of long-COVID patients.

PATIENTS AND METHODS: In this study, we employed a proteomic-based approach utilizing mass spectrometry to analyze the serum of 81 patients with long-COVID syndrome. Moreover, viral integration in patients’ leukocytes was assessed with a preliminary study, without further investigation.

RESULTS: We identified the presence of the viral spike protein in one patient after infection clearance and negativity of COVID-19 test and the vaccine spike protein in two patients two months after the vaccination.

CONCLUSIONS: This study, in agreement with other published investigations, demonstrates that both natural and vaccine spike protein may still be present in long-COVID patients, thus supporting the existence of a possible mechanism that causes the persistence of spike protein in the human body for much longer than predicted by early studies. According to these results, all patients with long-COVID syndrome should be analyzed for the presence of vaccinal and viral spike protein.

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Friday, July 8, 2022

The Georgia Guide Stones, Covid-19, and Original Antigenic Sin

I enter the above heading in the contest for the world's most obscure blog post title, a title that I will now attempt to explain. 

The Georgia Guide Stones, as any conspiracy theorist knows, were 19-foot-tall slabs of granite erected in a farm field in the US State of Georgia, inscribed with globalist directives including the injunction to eliminate nine tenths of the world's population, while selectively breeding the posterity of the remainder. These stones have now been taken down, the first with an explosive laid by an unknown hand, the rest with a backhoe presumably on orders from Georgia State authorities. 

In what way could Covid be related to the Georgia Guide Stones? Simply on the presumption that the virus is the intended mechanism for global depopulation. 

But how can that be, since the Covid mortality rate is so low? The answer could be what is known in the technical literature as original antigenic sin (OAS).

Original antigenic sin is the whimsical name for a particular feature of the action of the human immune system. What is it? The answer is fairly straight forward, but, as set forth below, the explanation has a number moving parts. 

On first infection by a pathogenic organism, the immune system develops proteins, known as antibodies, that bind to one or more constituents of the alien organism thereby inactivating it. The constituents of the pathogen in response to which antibodies are formed are known as antigens. Thus, for example, infection by the SARSCoV-2 virus, aka Covid-19, elicits the production of antibodies to various protein constituents of that particular virus. Best known among Covid-19 antigens is the infamous spike protein, which enables the virus to enter human cells, while damaging the affected tissues in the process. 

The antibodies that the immune system evolves in response to the presence of an antigen, bind to the antigen, thereby preventing it from serving its function, whether that be, in the case of a viral antigen, the invasion of the cells of the host organism or in the replication of the virus once cell entry has been achieved. 

Having created an antibody, a process that may take several weeks during which viral infection can proceed, the immune system retains cells, known as memory B-cells, that are capable of producing the same antibody on short notice in the event of a future infection. That is the essence of disease immunity, and is the phenomenon upon which the effectiveness of vaccination against infection depends. In vaccination, a pathogen-derived antigen, or a non-infectious form of the pathogenic organism, is injected to induce the production of pathogen-specific antibodies resulting in long-lived disease immunity. 

Original antigenic sin results when infection by a particular pathogen is succeeded by infection by a evolved version of the same pathogen in which the antibody-inducing antigen, for example the spike protein in the case of Covid-19, differs due to mutation from the immunity inducing antigen of the earlier infection or vaccination. What happens then is that the mutated antigen evokes rapid production of antibodies effective against the original antigen. This reaction is a sin if the mutation in the antigen of the newly infecting pathogen prevents effective binding by the antibodies to the original antigen, which are what the host organism is producing. In that case, the immune system kicks into high gear producing antibodies that don't work.

Here then is how OAS could be exploited to cut a huge swathe through the human population. 

First, let loose a virus such as Covid-19 that is both highly infectious and sufficiently scary to compel universal vaccination. 

Next, release a novel strain of the virus with mutations that massively increase virulence while modifying the antigen against which the vaccine-induced antibodies are effective (the spike protein in the case of Covid-19 mRNA vaccines) in such a way that it resists binding by the vaccine induced antibodies. 

The result? The immune system goes into overdrive producing ineffective antibodies, and people die by the billion. 

The above conspiracy theory is just that, a theory, without any supporting evidence that I am aware of. But it does demonstrate that we live in interesting, and dangerous, times. 


Related:


Since COVID “Vaccines” Were Unleashed, Athlete Deaths Are Up 1700% 
Best not be an athlete then (Big Pharma spox)

Covid Vaccine Boosters Are Killing One in Every 800 Over-60s and Should Be Withdrawn Immediately, Says Leading Vaccine Scientist

EU Parliament Member Drops Nuke on Universal COVID Vaccine Campaign – “This is the WORST Crime Ever Committed on Humanity” (VIDEO)

Beijing Scraps China's First COVID Vaccine Mandate In Just 48 Hours After Furious Social Response

Natural Immunity 97 Percent Effective Against Severe COVID-19 After 14 Months: Study

Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

More Vaccines, More Infections: Scotland Has 50% Higher Infection Rate Than England Despite Being More Highly Vaccinated, Data Show Original Antigenic Sin?

Twitter Admits it Was Wrong to Ban Alex Berenson and Reinstates His Account in First Ever Tech Censorship Legal Dispute Climbdown 
(Alex Berenson on Substack)

8.3 Million People in England on Antidepressants After Lockdowns, Up 7% in One Year Blimey! The whole country's going nuts. Those whom the gods, or globalists, would destroy, they first make mad. Come on folks: fight back and you'll feel better. 

Another Conspiracy Theory: COVID, Capitalism, Friedrich and Boris

Mosquitoes Testing Positive to Rare, Deadly Viruses in US Months After Bill Gates Released Millions in The Wild

Thursday, February 24, 2022

Omicron Thwarts Some of the World’s Most-used COVID Vaccines: BRAVO

Omicron thwarts some of the world’s most-used COVID vaccinesAnd that's not surprising. The vaccines induce the production of an antibody that inactivates the spike protein. That is, the spike protein of the original Wuhan Covid strain. But the spike protein of the Omicron variant is highly mutated, which means that the antibody induced by the vax doesn't bind effectively to the Omicron spike protein: hence little or no benefit from the vax.

But not to worry.  Dr Angelique Coetzee, the South African doctor who first spotted the new Covid variant Omicron, says the patients seen so far have had mild symptoms. Thing is, though, that infection with Omicron will induce antibodies not just to the highly mutated Omicron spike protein, but all 17 other proteins possessed by the virus. 

This antibody response is relatively short-lived, just like the Covid vax that needs to be repeated every few months if it is to remain effective. However, infection by Omicron creates memory cells that record both the genome of the virus and the recipe for all the antibodies that the immune system created in response to the infection. That means that the immune system will promptly recognize a future infection by any Covid strain, however mutated. Furthermore, the immune system will retain a memory of the antibodies it needs to destroy the virus and will, thus, begin pumping those out much sooner than if  faced by a previously unknown virus. 

What this means is that Omicron, whether naturally occurring or created anonymously in the lab, will serve as a live vaccine. As it spreads throughout the population, it will greatly reduce the incidence of severe illness due to Covid. Covid then will join the collection of viruses that cause what is known as the comon cold.

So good-bye Covid. Good-bye the vax. Welcome back bad winter colds. Oh and good-bye to vax passports and the Western version of China's Social Credit system of totalitarian social control -- for now. But never forget the enthusiasm of Western dictator-wannabes, when they believed totalitarian control was within their reach. 

Related: 

COVID Deaths Worldwide Were Greatly Overstated


Pfizer's COVID-19 Vaccine Goes Into Liver Cells And Is Converted To DNA: Study

Pfizer 5-11 Vax has NEGATIVE Effectiveness After Just Over a Month Yeah, but it makes money for investors and it gives the public health people a means to keep the public in a state of subservience and panic

UK Covid vaccine death or injury claims could hit £110m

New Zealand High Court: Vaccine Mandate Not "Demonstrably Justified", Breach Of Rights

Iceland Wants ‘As Many People as Possible’ to Catch Covid-19 After Ending All Restrictions – Suggests Vaccine is Not Enough

Friday, November 5, 2021

The Covid Hoax: Italy Cuts Official Death Toll by 97%

Remember early 2020, when the virus that had the Chinese dropping and twitching in the streets went global, causing mass death and hospital chaos in Northern Italy and worldwide panic, with folks locked-down, and in China even welded, in their homes to stop the spread.

Well it was all lies. 

Of the mass Covid deaths reported in Italy, 97%, Italy's Institute of Health now reports (and here), were "with Covid" not "by Covid". 

But the waves? What about the waves? The multiple epidemic waves?

All rubbish. Epidemic pathogens don't do waves. Waves are the creation of bogus PCR tests and lockdowns that promoted household transmission of the synthetic Corona virus (that is, a virus of the common cold family) of limited virulence.

But in that case, why? 

Hysteria?

Hysteria of the political class? 

For sure, they're mostly brain dead, clowns or wannabe dictators: President Brandon, BoJo, Justin Trudeau, New Zeland's zero-Covid fanatic, and the inimitable, no longer New South Wales Premier, Gladys Berejiklian.

But there's been one absolutely consistent theme: Get The Vax. 

No Vax no job, no rights, just stay quarantined at home forever and die for lack of food for all Gnome Chomsky or anyone in government cares.

But why the Vax?

To save your life. 

Save it from what? A virus that didn't kill almost one hundred thousand Italians, but just 3000 -- fewer than typically die from the flu each year?

A vax that doesn't stop the spread — it clearly promotes the spread (see Table 2 on Page 13, of this UK Covid-19 Vaccine Surveillance Report, Week 42)?

Surely, it has to be the Vax: the vax with the spike protein that can enter the nucleus of any  cell, liver, brain, skin, testicle or ovary, and disrupt the the machinery of DNA damage repair.

That's the machinery that prevents your genetic blueprint from getting scrambled. Once that's disrupted, expect trouble. Big trouble: every conceivable metabolic disease, plus cancer and sterility. 

Yes, well, as Prince Charles, Britain's leading politician, reiterated among his jet-setting friends at COP26 (aka Cut Our Population), we have to place ourselves (i.e., you, not my jet-setting friends) on a lower and more sustainable course. 

How? 

Have lot fewer of you, obviously. 

Could we then already be on that "more sustainable" course, embarked now, thanks to the vax, on a great dying? 

Related: 

More than 38 million people worldwide have been infected with the coronavirus, and as of Monday (i.e., October 12, 2020), fewer than five of those cases have been confirmed by scientists to be reinfections.

When will the CDC correct its COVID death counts, as Italy just did?

Pfizer says it's at-home Covid pill cuts risk of death by up to 90%
So, as our genius Prime Minister in Ottawa should be able to figure out: just buy some pills and end the stupid vax mandate

Science Shows Vax Mandates Are Stupid



San Francisco Announces Vaccine Mandate for All Children 5 and Older




Californian Town Declares Itself a Constitutional Republic to Oppose the State’s Covid Laws

Wednesday, November 3, 2021

SARS–CoV–2 Spike Protein Impairs DNA Damage Repair — Or How Covid-19 Was Designed to Kill You?

 Here's the paper in the journal Viruses:

SARS–CoV–2 Spike Impairs DNA Damage Repair ...

Hui Jiang 1,2,* and-Fang Mei 2

1. Department of Molecular Biosciences, The Wenner–Gren Institute, Stockholm University, SE-10691 Stockholm, Sweden

2. Department of Clinical Microbiology, Virology, Umeå University, SE-90185 Umeå, Sweden

.... Here, by using an in vitro cell line, we report that the SARS–CoV–2 spike protein significantly inhibits DNA damage repair .... Mechanistically, we found that the spike protein localizes in the nucleus and inhibits DNA damage repair by impeding key DNA repair protein BRCA1 and 53BP1 recruitment to the damage site. Our findings reveal a potential molecular mechanism by which the spike protein might impede adaptive immunity and underscore the potential side effects of full-length spike-based vaccines. ...


So note:

1. It's the spike protein they want to inject you with.

2. The spike protein can get into the nucleus of any cell and disrupt the machinery that prevents the genome from getting scrambled.

3. Scramble your genome and your done. 

But you still want your kid vaxxed? 

Go ahead.


Acknowledgement:
Above links via WhatReallyHappened

Related:



'Falsified Data': Pfizer Vaccine Trial Had Major Flaws, Whistleblower Tells Peer-Reviewed Journal

PROFS: MARTIN KULLDORFF AND JAY BHATTACHARYA: How Fauci Fooled America:
In the UK 85% of Covid-19 deaths are among the Vaccinated, Child deaths have risen by 83% since they were offered the jab, the Covid-19 Vaccines have negative effectiveness as low as -132%

Wednesday, October 20, 2021

Clinical Pathologist: The Spike Protein, Which Is the Active Vax Agent, Causes Irreversible Tissue Damage


Related:

NIH Admits Funding Gain-Of-Function COVID Experiments; Gives EcoHealth Five Days To Report Data:
"A top NIH official admitted in a Wednesday letter that the US-funded so-called "gain-of-function" research in Wuhan, China - and that the US nonprofit which conducted it, EcoHealth Alliance - led by the controversial Peter Daszak, "failed to report" that they had created a chimeric bat coronavirus which could infect humans. ..."

Official Government Docs Comparison Suggests “Fully Vaccinated” Are Developing AIDS (Sounds like insane fabrication. Or Armageddon has arrived.)

 Top scientists release study warning against COVID-19 vaccines, demand an immediate end to vaccinations


Why the Media Doesn't Question the Vax:

Dozens of workers at Los Alamos nuclear lab sue over vaccine mandate

Covid Deaths Before and After Vaccination Programs:

Natural Versus Vaccine Immunity:

Monday, May 3, 2021

Adverse Reactions to mRNA Covid Vaccines

 The mRNA "vaccines" against Covid19 deliver the genetic information that the virus uses to produce the so-called spike protein. This information is encoded in the sequence of ribonucleic acid bases that make up the mRNA molecule. 

The spike protein caps the spikes on the Covid19 virus particle and adheres quite specifically to certain of the cells (ACE2 receptors) of the epithelium that lines the lung. 

Once attached to an ACE2 receptor, the virus injects its genetic material into the cell. Thereupon, all components of the virus, not just the spike protein, are manufactured by the machinery of the host cell and self-assemble to create a mass of new virus particles. 

The information delivered to the cell (any cell in the body) in the form of an mRNA Covid19 "vaccine" is processed by the cell's protein synthetic machinery to produce spike protein. The spike protein is then  recognized by the immune system which, in response, produces antibodies that inactivate the spike protein of invading Covid19 virus particles, thereby resisting infection. 

Very clever. 

Except, among other things, it turns out that the spike protein is responsible, wholly or in part, for the symptoms of Covid19 disease, as just reported in the journal Circulation Research. What that means is that the mRNA vaccines may mitigate against Covid19 infection, or in the event of infection, Covid19 disease. However, it may itself cause lung injury and illness in the complete absence of the virus. 

Cf.


Garudian: Covid is doing the job: US birth rate sees biggest fall for nearly 50 years

Gateway Pundit: Most Vaccinated Country on Earth Closes Schools and Sports as COVID Cases Surge — 35% of New Cases Are Fully Vaccinated Residents

Reuters: Denmark Ditches J&J COVID Vaccine, Says Benefits ‘Do Not Outweigh Risk’ of Blood Clots

Salk Institute: The novel coronavirus’ spike protein plays additional key role in illness

Circulation Research, April 30, 2021: SARS-CoV-2 Spike Protein Impairs Endothelial Function via Down Regulation of ACE2

British Columbia further restricts use of Astra Zeneca Covid "vaccine" due to concern over induced blood clots

India Today: Bill Gates believes Covid 19 vaccine tech should not be given to India, what he said and why he said it