Monday, May 3, 2021

Adverse Reactions to mRNA Covid Vaccines

 The mRNA "vaccines" against Covid19 deliver the genetic information that the virus uses to produce the so-called spike protein. This information is encoded in the sequence of ribonucleic acid bases that make up the mRNA molecule. 

The spike protein caps the spikes on the Covid19 virus particle and adheres quite specifically to certain of the cells (ACE2 receptors) of the epithelium that lines the lung. 

Once attached to an ACE2 receptor, the virus injects its genetic material into the cell. Thereupon, all components of the virus, not just the spike protein, are manufactured by the machinery of the host cell and self-assemble to create a mass of new virus particles. 

The information delivered to the cell (any cell in the body) in the form of an mRNA Covid19 "vaccine" is processed by the cell's protein synthetic machinery to produce spike protein. The spike protein is then  recognized by the immune system which, in response, produces antibodies that inactivate the spike protein of invading Covid19 virus particles, thereby resisting infection. 

Very clever. 

Except, among other things, it turns out that the spike protein is responsible, wholly or in part, for the symptoms of Covid19 disease, as just reported in the journal Circulation Research. What that means is that the mRNA vaccines may mitigate against Covid19 infection, or in the event of infection, Covid19 disease. However, it may itself cause lung injury and illness in the complete absence of the virus. 

Cf.


Garudian: Covid is doing the job: US birth rate sees biggest fall for nearly 50 years

Gateway Pundit: Most Vaccinated Country on Earth Closes Schools and Sports as COVID Cases Surge — 35% of New Cases Are Fully Vaccinated Residents

Reuters: Denmark Ditches J&J COVID Vaccine, Says Benefits ‘Do Not Outweigh Risk’ of Blood Clots

Salk Institute: The novel coronavirus’ spike protein plays additional key role in illness

Circulation Research, April 30, 2021: SARS-CoV-2 Spike Protein Impairs Endothelial Function via Down Regulation of ACE2

British Columbia further restricts use of Astra Zeneca Covid "vaccine" due to concern over induced blood clots

India Today: Bill Gates believes Covid 19 vaccine tech should not be given to India, what he said and why he said it

21 comments:

  1. "An advanced society functions by creating a series of institutions, telling them what it wants them to do, and funding them to do it. Institutions like the police, fire departments, courts and schools do the jobs society creates them to do. But one American institution—higher education—has decided to repurpose itself. It has set aside the job given to it by society and substituted a different one."

    I love the WSJ, but sometimes you have to watch out for the editorial page. This is one of those times-- this comment is naive, and perhaps with premeditation.

    Advanced society tells its institutions what to do-- even higher education. The problem is, advanced society is not democratic. It is plutocratic. The plutocrats are telling higher education to switch gears now...It wouldn't happen otherwise.

    The professors and administrators--God love them-- are so easily pushed around. They understand where their "funding" comes from and won't stand on any principle. The ones who are aware their principles are being violated won't speak out. They'll stand around saying, "Well, what would you have me do?"

    You can't say--Don't Allow Yourself To Be Pushed Around. They wouldn't understand.

    In general you can't expect anyone to understand what would cause them to lose their meal ticket if they did understand. When you're talking about the average university president or administrator, it is a deluxe meal ticket, too.

    I don't think many people remember the loyalty oaths university professors were forced to sign back in the fifties, or the strict enforcement of ideology-- cold war ideology-- on university campuses back then. Or the horrific level of conformity, even intellectual. (There were exceptions and bright lights and that's what we choose to remember. Yeah, because that's the only stuff worth remembering.)

    I saw a bulletin just the other day, sent out from the president of the University of New Mexico to his faculty. They were being asked to attend seminars to sort out their "micro-aggressions". Their micro-aggressions mainly consisting in not wanting to have the crap ideology now being dispensed shoved down their throats.

    But from the plutocrats' viewpoint, see the beauty of this. We probably need all the aggression we can summon not to be led to slaughter, which appears to be where we're all headed.

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    1. I just replied to that -- at length. But fucking Blogger deleted it. Apparently, if I am logged into my Google account, Blogger deletes whatever I say. Well done Google.

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    2. Apparently, I have to log out of my account, make my comment and then, when I hit "Publish" I have to log back into my Google Account. Is that stupid, or what?

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    3. Anyway, the gist of what Google deleted on my first attempt:

      In England, during the early years following WW2, universities were generally headed by distinguished scholars. Thus, for example, in 1964, I was personally graduated at a minor provincial university by a small grey-haired gentleman named Edgar Adrian, Nobel Laureate and President of the Royal society.

      There was nothing exceptional about this. Post war Britain was still being run as it had been in the days of imperial greatness, which is to say that, as a rule, only truly able people were deemed fit to take ruling positions in society.

      I wrote about this in a blog post entitled:

      The Rot At the Head of the University This was disappeared by the Google search engine, although Bing faithfully returns it at the head of the list of search results.

      In North America, universities have always been subject to a heavier political hand. But during the post WW2 era, the consequent damage was negated by:

      First, the fear among those of the political class of the Soviets and the consequent hope that the university would be a source of technological innovation which would beat whatever the Commies could devise. Thus academics were given considerable freedom to manage their affairs as they saw fit;

      Second, fear among those of the academic community of the Soviets, from which many were refugees, and hence a shared interest with the political class that reduced friction between the owners of the university and the scholars whose toil served the interests of the owners.

      But with the advent of the vandals, the likes of Bliar, Cameroon, and BoJo, things changed.

      My old school is now headed by a political hack, a former technical school lecturer turned politician who served in Parliament as an assistant to Tony Blair. Not surprisingly, my alma mata has slumped in standing as a research institution.

      Meantime, in North America, all members of the diaspora of European scientists have long retired and are mostly dead. Hence the precipitous decline fo the American university into intellectual depravity or outright lunacy.

      We are doomed. Ruled by very rich morons, who value the pleasure of telling everyone what to do, over the survival of their civilization -- if you can call it that.

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    4. I had to come back here and thank you for offering me a perspective I'd never considered before. I am very interested in this topic.

      For some reason, this made me think of William James's essay The PhD Octopus:

      https://www.uky.edu/~eushe2/Pajares/octopus.html

      I look forward to reading your essay.

      Too bad about losing the more detailed comment.

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    5. Re: William James' essay on the PhD degree

      James would surely have enjoyed Stephen Leacock's remark that PhD stands for Philled Up.

      But apart from magically "qualifying" me for a number of the jobs I took before opting to work for myself, the title has proved useful at times. As when my wife was in hospital and I wanted immediate action from an idle doctor and I informed his office that it was Dr. ... calling. Immediate action followed.

      In Britain's academic world, though, there used to be a tradition that the really bright need not bother with a Ph.D. Among my biochemistry profs was a 21-year old from Oxford, who went on to become a university vice chancellor, head of the Downing St. think tank under Margaret Thatcher, then Director of the LSE, before more or less retiring as a Professor of the History of Science.

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  2. While I was over at the WSJ looking at that article, I noticed they WSJ reporters had posted a nice video about the price of coffee. Did you happen to notice it?

    According to the report, coffee is currently somewhat underpriced, but is poised to increase dramatically over the next few months. (Makes me consider stocking up.)

    The reasons for the increase were the main topic. While the disruption of supply lines and distribution chains due to the pandemic were briefly mentioned, the emphasis was on climate change. (Other factors were also discussed, which I appreciated, greatly.)

    I couldn't help wondering though. The quantity of effect caused by the various factors was left to the viewer's subjective interpretation. Was the effect of the pandemic disruptions really as minor as its brief presentation suggested? Was the effect of climate change as significant as its longer presentation suggested?

    I'm afraid, CS. I can see how the ill effects of the plandemic can be presented as the effects of other things, such as "second waves" and climate change. And this to the advantage of our buddies the plutocrats. (As you may know, Bill Gates is now a climate change expert.)

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    1. Can a society build on bullshit long survive?

      All this crap will surely be swept away. The only question is how.

      Suppose China, with their purpose-build ballistic missiles, were to take out a bunch of US aircraft carriers, plus Britain's one and only carrier, as they cruise threateningly off China's coast, what would happen.

      Would we have WWIII, or would the shock induce a second American Revolution, and a return to rational government?

      And, do you think that the divorce of the Gates's is a tax avoidance measure?

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    2. "And, do you think that the divorce of the Gates's is a tax avoidance measure?"

      Just plain shocked, CS. I hadn't heard a thing. At this time...Wow. Last I knew he and Melinda were snickering over how people would listen to them next time. I've been expecting weird things to start happening to Mr. Bill, but not this.

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    3. Holy bat farts, that makes a lot of sense.

      Another thing I saw at the WSJ recently was a banner headline: "Everything Screams Inflation." Beneath, among the first few lines was the claim, I think a very true one, the average investor is wholly unprepared for this.

      I wouldn't know how to prepare for it, either. I have been entirely flat-footed for quite a few years as I have been unable to make heads or tails out of what's going on in the markets, except to see they're being manipulated by extremely powerful behind-the-scenes forces. The most I've been able to do is read what might be to the advantage of whoever or whatever that is, and play it, if I can morally stomach to do so.

      A lot of terrible things are playing out in the world right now. I am almost glad you let this post linger awhile, for it has allowed the implications of these things to settle. This is potentially nightmare city we're living in right now.

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  3. That article from India was extremely interesting to me. It is oddly structured, but what came out for me was the understandable sensitivity of the people of India to any form of imperialism. They know how the game is played. They aren't stupid. Neither politically or technologically. (They have a lot of problems as a society, but they aren't exactly caused by low I.Q.) They don't wish to be the jewel in anyone's crown, even Bill Gates's. It is so damned obvious his real motive is to make money. He could responsibly arrange the technology and patent transfers to India if that were in his interest. (But after they'd be able to make their own drugs, what commendations would Mr. Bill, Uncle Sam, or the British Bulldog receive for their "charitable" "humanitarian" "donations"?)

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  4. Look at this, CS:

    "The very first vaccines for COVID-19 to complete phase 3 testing are an entirely new type: mRNA vaccines. Never before have mRNA vaccines — such as the two-dose Pfizer/BioNTech and Moderna vaccines that have now received emergency use authorization from the FDA — been approved for use in any disease."

    https://www.health.harvard.edu/blog/why-are-mrna-vaccines-so-exciting-2020121021599#:~:text=The%20very%20first%20vaccines%20for,use%20in%20any%20disease.

    An entirely new type. They're injecting the entire world population with "an entirely new type."

    Mr. Bill knows a thing or two about problems with the Beta. In fact, usually the Beta is used to better iron out the problems in the final, marketable version. God help us. They're injecting the human race with the Beta.

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    1. Plus we have Elon's full self-driving beta to look out for.

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  5. "The information delivered to the cell (any cell in the body) in the form of an mRNA Covid19 "vaccine" is processed by the cell's protein synthetic machinery to produce spike protein."

    I don't think the mRNA is taken up by any cell in the body. According to the Harvard summary:

    "What if you injected that mRNA into someone, and the mRNA then traveled through the bloodstream to be gobbled up by immune system cells, and then those cells started to make the spike protein? Would that educate the immune system?"

    The mRNA is gobbled up specifically by immune system cells, and then immune system cells begin to make the spike protein, presumably to educate future immune system cells.

    It makes sense to me only immune system cells would admit the mRNA. RNA is a fairly large molecule as it is, and the mRNA they are using is encased in something to protect it from damage in the human bloodstream. My opinion is this combination would render it impermeable for most cells.

    There's quite a bit I don't understand, though.

    If the immune system involved in gobbling up the mRNA is making a spike protein recognized by the immune system as an antigen, why doesn't this potentially lead to an autoimmune reaction, the immune system attacking the immune system?

    The spike protein is produced within the immune system cells, how is it expressed? For the spike protein thus produced, it would have to be in some form to "educate" the immune system against the spike protein, but how precisely could this be? If the spike protein is expelled--and I guess this must be the mechanism-- it could be engulfed by other immune cells which would then recognize the spike protein and thus the Covid coronavirus without producing more spike protein and thus a cascading effect.

    It isn't hard to imagine things going wrong. Even if there is extensive R&D backing this up, I wouldn't want to be associated with exposing the world's population to it without the most rigorous testing. Obviously the Covid19's severity is not sufficient to warrant this risky procedure. We'll see what we'll see...

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    1. Where the vaccine mRNA is processed is a question that has lurked vaguely in the back of my mind. According to this short review, the injected mRNA can be taken up by a variety of cells, including liver, spleen, muscle and epidermal cells. How then the protein for which the "vaccine" mRNA codes comes to the attention of the B cells, I'm not at all sure.

      I am attempting to inform myself by reading an immunology text, Roitt, Fifteenth Edition: Ugh! Horrible. It begins with six pages of abbreviations--very encouraging. The first chapter then begins with a sentence of almost eighty words. The style is horribly anthropomorphic. Apparently students today can understand nothing unless it is rapped in a cliche.

      If I were an undergraduate today, I would be bottom of the class. Such texts don't deserve to be read and if can surely only be read by drones with no real interest in science. But for an intellient student, the challenge of translating such muck into concise scientifically correct statements is just too much to expect. And every course will have its own two kilograms of god aweful text to be somehow internalized.

      How horrified would William James have been to know that this is where American education would lead.

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    2. "Let’s dive into some details. But while doing so, I need to note up front that not all of these details are completely known, immunology being what it is."

      This is from the short review to which you linked. Thanks for that.

      Well, the details really should be fully known before injecting the entire world and creating a situation in which human beings are used as guinea pigs. We objected to the Nazis doing these things, but now here, as in so many other areas, we surpass the Nazis.

      Did you notice how gleeful those Harvard boys were about the mRNA being the "exciting new thing"? The "science" blurb was almost an advertisement. They're proud to be at the forefront-- they've gleefully thrown all caution to the wind.

      Also, their description was a bit misleading. It matters if so many other tissues will be absorbing the mRNA and releasing the spike protein. What happens if in some tissues the spike protein becomes lodged in the cell membrane? Does that cell get attacked?

      We have learned about the alarming rise in auto-immune illness in recent years. The potential here-- and who knows-- certainly exists.

      I am thankful someone else out there sees some of this for what it is, CS. I have a friend who is a professor of infectious diseases, and I am never, ever going to talk to him again. He is utterly thoughtless and at the same time incredibly vain. He is just very self-satisfied, and a know it all. (I'm sure he is competent as a doctor.) Yet he will be churning out the new M.D.'s, putting his stamp on their concept of expertise.

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  6. If the immune system cells are expelling the spike protein they produce using the "vaccine" mRNA and the spike protein itself causes the symptoms of Covid19, how many people are out there will have immune systems producing more spike protein than needed to "educate" the rest of the immune system? Once again I see this idiotic "one size fits all" solution to a problem which certainly will turn out to be many-dimensioned. There is considerable genetic variation in the global population of humanity.

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    1. Yes, the spike protein is apparently the cause of Covid19 induced blood clots. That the "vaccine" induces production of spike proteing thus presumably explains why some recipients of the "vaccine" promptly drop dead or suffer other negative effects.

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  7. Concerning the divorce of the Gates's, could Bill's Epstein relationship be a factor.

    Did our wise and beneficiant super rich man share Augustus Caesar's lust for deflowering your girls?

    Could that be the reason Bill, at pal or blackmailer Jeffrey's direction, gave millions to the director of the MIT media lab.

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